Reply to: Covid-19 and Carbon Monoxide

[DoctorStrangelove]

Remember: don't try to smoke whilst on oxygen.

It doesn't end well.

[Mordac]

As soon as smoker is admitted to hospital they will generally deny that they are are smoker, that alone will bugger up statistics.

Corona viruses have been around for many years. Why should Covid-19 react any differently to carbon monoxide?

If they ask to be wheeled outside every couple of hours, the stats people should be able to work out what's going on...

[OwlHoot]

As soon as smoker is admitted to hospital they will generally deny that they are are smoker, that alone will bugger up statistics.

Yes, I'd concede that may very well be a significant effect.

But if tobacco is as bad as they say then can't a chest X ray show up who has been smoking?

[Mordac]

You forgot to mention that tobacco is a vegetable and smoking is one of your five a day healthy diet

It's about twenty of mine...

[Paddy]

As soon as smoker is admitted to hospital they will generally deny that they are are smoker, that alone will bugger up statistics.

Corona viruses have been around for many years. Why should Covid-19 react any differently to carbon monoxide?

[OwlHoot]

2020-06-08 MORE evidence smokers are at less risk of Covid-19: Study of 90,000 infected patients in Mexico reveals adults addicted to cigarettes are 23% LESS likely to catch the virus

* The research also showed smokers are less likely to suffer adverse outcomes

* It adds to the theory that smokers are somehow protected from the coronavirus

* International researchers have reported a low prevalence of smokers in patients

* Scientists say nicotine may be able to block the coronavirus from entering cells

* Doctors are keen to start trials of nicotine patches, but advise kicking the habit

[Paddy]

2020-04-06 COVID-19 morbidity and mortality caused by endogenous carbon monoxide poisoning, with recommendations for testing and treatment



Glad to see someone is on the case

P.S. "Endogenous" means "produced internally by the body", just as I surmised, as opposed to "exogenous".

You forgot to mention that tobacco is a vegetable and smoking is one of your five a day healthy diet

[AtW]

How many smokers were among those so-called scientists? We must know the TRUTH!

[Paddy]

2020-06-02 More evidence smokers are at less risk of Covid-19: Scientists discover adults who are hooked on cigarettes are 50% less likely to test positive for the illness

But you conveniently missed out from the same article

But British scientists have previously debunked the theory, finding the opposite

[OwlHoot]

2020-04-06 COVID-19 morbidity and mortality caused by endogenous carbon monoxide poisoning, with recommendations for testing and treatment

Abstract

To test our hypothesis that abnormal levels of endogenous carbon monoxide (CO) produced naturally by heme oxygenase-1 (HO-1) in response to infections of all kinds may be contributing to the morbidity and mortality associated with COVID-19, we searched PubMed for peer-reviewed literature on carbon monoxide and each of eleven abnormal blood tests, fourteen signs and symptoms, and five fatal complications of COVID-19 infection reported in a case series from a hospital in Wuhan, China: acute respiratory distress syndrome (ARDS), acute kidney injury, acute cardiac injury, arrhythmia, and shock.

We found reports of acute exogenous CO poisoning causing all the same signs, symptoms and complications, and all the abnormal blood tests except D-dimer and procalcitonin. Our search also found endogenous HO-1 and CO levels correlated with these complications, independent of any inhaled CO exposure.

In sharp contrast to the CO poisoning literature, most studies of endogenous CO interpret its close positive correlation with these acute conditions as protective, with some going so far as to recommend treating ARDS with inhaled CO. We conclude with new recommendations for testing endogenous CO poisoning in COVID-19 cases using devices approved by the US Food and Drug Administration that can distinguish CO coming from the lungs, arteries, veins, and average of all tissues, unlike current protocols for CO poisoning that only measure CO in arteries or veins but not both.

Based on these findings, we appeal to clinicians to start testing CO levels in COVID-19 patients and to stop monitoring oxygen saturation with conventional pulse oximeters that overestimate oxygen saturation by the sum of carboxyhemoglobin and methemoglobin. We conclude by reviewing FDA-approved treatments that may help COVID-19 patients with endogenous CO poisoning. These include zinc-based drugs that lower the rate of endogenous CO production by inhibiting HO-1, and drug-free devices and methods that reduce the total body burden of CO after exogenous CO poisoning.

Glad to see someone is on the case

P.S. "Endogenous" means "produced internally by the body", just as I surmised, as opposed to "exogenous".

[DealorNoDeal]

Perhaps smokers are more fearful of catching cv19, so are more mindful of social distancing.

Or, perhaps it's just because smoking is so bloody anti-social.

(I'm a pariah smoker btw)

[OwlHoot]

2020-06-02 More evidence smokers are at less risk of Covid-19: Scientists discover adults who are hooked on cigarettes are 50% less likely to test positive for the illness

* Israel researchers looked at 3 million people, of which 4,500 had coronavirus
* They found 10 per cent of patients who had tested positive were smokers
* But in the general population, 19 per cent had the habit
* The researchers reported a seemingly 'genuine' protective effect of smoking
:::

[Paddy]

WHO statement: Tobacco use and COVID-19

Tobacco smoking is a known risk factor for many respiratory infections and increases the severity of respiratory diseases. A review of studies by public health experts convened by WHO on 29 April 2020 found that smokers are more likely to develop severe disease with COVID-19, compared to non-smokers.

COVID-19 is an infectious disease that primarily attacks the lungs. Smoking impairs lung function making it harder for the body to fight off coronaviruses and other diseases. Tobacco is also a major risk factor for noncommunicable diseases like cardiovascular disease, cancer, respiratory disease and diabetes which put people with these conditions at higher risk for developing severe illness when affected by COVID-19. Available research suggests that smokers are at higher risk of developing severe disease and death.

WHO is constantly evaluating new research, including research that examines the link between tobacco use, nicotine use, and COVID-19. WHO urges researchers, scientists and the media to be cautious about amplifying unproven claims that tobacco or nicotine could reduce the risk of COVID-19. There is currently insufficient information to confirm any link between tobacco or nicotine in the prevention or treatment of COVID-19.

[NotAllThere]

If truth is spelt "TRUTH", you know it's bollox.

[CheeseSlice]

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