never use .com

[Paddy]

Never choose a US .com .net or .org etc domain otherwise it may get you in real trouble.

Verisign has issued a statement to The INQUIRER regarding ICE's claims that it has jurisdiction over all .com and .net domain names based on the fact that Verisign, the internet registry in charge of .com and .net TLDs, is a US-based firm.In it the firm states that it cooperates with law enforcement authorities when presented with a court order.
Source: The Inquirer (US claims all .com and .net websites are in its jurisdiction - The Inquirer)

BBC News - TVShack website: Petition in support of Richard O'Dwyer

The Sheffield Hallam University student said he was "surprised" when police officers from the UK and America seized equipment at his home in South Yorkshire in November 2010.

The case was brought by the US Immigration and Customs Enforcement agency, which claims that the TVShack.net website earned "over $230,000 in advertising revenue" before US authorities obtained a warrant and seized the domain name in June 2010.

[AtW]

Paddy is right - don't use .COM or .NET if you intend to do things for which in US you might end up in jail for.

Other than that it's fine to use them.

[xoggoth]

I wonder if it would make you more easily sued over, say, copyright infringement by your own content or damage by a download?

[d000hg]

AtW maybe you could generate a new income stream if you registered majestic12.xxx?

[wim121]

The xxx domain is far too expensive for lewd websites to adopt. Don't see the point in it unless it comes down in price.