Alcohol

[Moscow Mule]

I though livers in alcoholics grew to ginormous sizes?

No, they shrink to a tiny size...

http://www.emedicinehealth.com/cirrhosis/article_em.htm

The liver may be injured by a single event, as in acute (new, short-term) hepatitis; by regular injury over months or years, as in biliary tract blockage or chronic hepatitis; or by continuous injury, as in daily alcohol abuse.

The liver responds to cell damage by producing strands of scar tissue that surround islands (nodules) of healing cells, making the liver knobby.
At first, the inflammation in the liver causes it to swell. As the disease progresses and the amount of scar tissue in the liver increases, the liver will actually shrink.
The scar tissue presses on the many blood vessels in the liver. This interrupts flow of blood to liver cells, which then die.
Loss of liver cells hinders the liver's ability to perform its normal functions.

[NickFitz]

The liver may be injured by a single event, as in acute (new, short-term) hepatitis; by regular injury over months or years, as in biliary tract blockage or chronic hepatitis; or by continuous injury, as in daily alcohol abuse.

The liver responds to cell damage by producing strands of scar tissue that surround islands (nodules) of healing cells, making the liver knobby.
At first, the inflammation in the liver causes it to swell. As the disease progresses and the amount of scar tissue in the liver increases, the liver will actually shrink.
The scar tissue presses on the many blood vessels in the liver. This interrupts flow of blood to liver cells, which then die.
Loss of liver cells hinders the liver's ability to perform its normal functions.

I need a drink after reading that...