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Another vote for Portable Apps. Great for client sites where you don't get Admin rights
On mine (all standalone/portable apps)
PStart (nice little GUI/launcher thing to keep it all in order)
Kitty (better than Putty, as it saves stuff in a local ini file)
CDBurnerXP
TeamViewer (remote access)
a-squared Free (spyware cleaner)
FireFox
Thunderbird
CCleaner
WinSCP
Screamer (internet radio)
Live Messenger
Winamp
PixaMSN